Cannabis y autismo

Today I’m writing about something that’s near and dear to my heart. Three years ago, my little brother and his wife had their first child. They were grade school sweethearts meeting each other in the 7th grade. After so many years together, they decided to tie the knot. When they finally got pregnant my family and I were so excited, we were full of anticipation. When Andrew came into the world I can���t describe how happy I was for my brother and his wife, my brother and I are 12 years apart so I watched him grow up. He became such a good man, frankly a better man than me and honestly I wanted him to. I grew up running the streets and didn’t want that for him. So when he had his son I couldn’t be more proud and happy. Later, after a couple years our little man was diagnosed with a mild case of Autism. My mom, being an old woman from the islands, was not sure what it was. She noticed something wasn’t right from early and when it was confirmed she was just as heartbroken as I was. Fear and worry set in but eventually we got used to him and his special funny antics. Recently, I was watching a special on CNN with Dr. Sanjay Gupta a world renowned doctor across the board. He became interested in the effects of medical marijuana and its positive effects on children with seizures, leading to his special on Charlotte Figi a young lady battling 30 seizures a day and a special cannabis oil blend now known as Charlotte’s web. That cannabis oil took her seizures down to one a week which allowed a better quality of life for her. Unfortunately, Covid took her life in 2020. Now, this new special on cannabis and its positive effects on Autism really hit close to home. He shared the story of another young lady suffering from severe Autism and how she would harm herself and do wild things that made it extremely difficult for her parents to take care of her. I sat up and watched that special in its entirety to gain as much knowledge as I could on the subject. The miraculous effects the cannabis oil had on her and the other families children was mind blowing! I learned a lot and it gave me so much hope. I can’t even begin to speak on how I feel about the powers that be, still imposing a federal problem with marijuana in the U.S. I’ll save that for another day! Today I count my blessings my nephew's case is mild and he is such a joy to be around. I love him so much and I look forward to his advancements in life. He is such a wonderful part of our family and I will someday get involved in creating a strain to help children too! … Oz

Read all about it here: https://www.leafly.com/news/health/cannabinoid-research-autism-2021

Weed near me.

Don’t forget to check out our NYC dispensary online at cigalar.com We have strains like Bubba kush, White runtz, Apple fritter, White truffle and so much more. Including accessories and edibles.

El Dr. Sanjay Gupta se suma al coro de la investigación del cannabis sobre el autismo en 2021

Emily Earlenbaughdiciembre 20, 2021

Un diagnóstico de autismo puede ser devastador para los padres, un trastorno del desarrollo neurológico que es incurable y, a menudo, difícil de tratar.

Muchos padres de niños con trastornos del espectro autista informan que los compuestos del cannabis a veces pueden ayudar. Pero exactamente cómo pueden ayudar los cannabinoides y cómo usarlos sigue sin estar claro, dado el siglo de bloqueo de investigación de EE. UU. sobre la 'marihuana'.

2021 saw some big advances in both research and visibility for this alternative treatment—from a CNN special on Sunday, to a clinicians’ conference in November that relayed reems of new research.

Autismo: incurable, en ascenso, un objetivo de la terapia con cannabis

Five key things toor ‘Autism Spectrum Disorder’ presents as a wide array of behaviors from mild to severe with cognitive deficits in things like talking, eye-contact, and/or repetitive behaviors.

• Its prevalence is now at 1 in 44 eight-year-olds in the US. It’s as high as 1 in 26 in California—where screening and robust services may have driven up diagnoses, the Washington Post reports.

• “Advanced parental age (particularly paternal age) has been identified as one of the most important risk factors of autism,” researchers have concluded. Mutations in over 100 genes controlling neurodevelopment seem to lead to malfunctional nervous systems in sufferers.

• En algunos casos, el sistema nervioso de señalización del cuerpo, el sistema endocannabinoide, parece fallar. Dado que el cannabis cambia la forma en que funciona el sistema endocannabinoide, los pacientes con TEA pueden beneficiarse, según indican los informes de casos.

• That’s important—since there are no FDA-approved drugs for core ASD symptoms, and only two for irritability.

explorar más Cannabis 101 información

El Dr. Sanjay Gupta echa un vistazo

One big step for cannabis’ visibility as a treatment for autism and its symptoms was the recent CNN special with Dr. Sanjay Gupta MD, WEED 6: Cannabis and Autism, which aired Sunday, diciembre 19.

En el especial, el Dr. Gupta entrevistó a varias familias que encontraron un éxito "milagroso" con el cannabis para los síntomas de autismo de sus hijos. Investigadores, médicos, pacientes autistas y sus familias detallaron cómo el cannabis puede cambiar la vida de las personas con TEA.

“Estamos viendo algunos cambios bastante impresionantes”.

Dra. Doris Trauner, profesora de neurociencia y pediatría en UC San Diego

“Estamos viendo algunos cambios bastante impresionantes”, dijo la Dra. Doris Trauner, profesora de neurociencia y pediatría en UC San Diego.

El Dr. Trauner dijo que la agresión de algunos niños autistas “ha desaparecido”.

Weed 6 se estrenó el domingo. (CNN)

“Quiero decir que se ha ido”, dijo el Dr. Trauner. “Muchos de los niños son más sociables”.

Fourteen states allow medical cannabis for severe autism, Dr. Gupta noted. Sometimes cannabis works for chronic, intractable, autism symptoms like self-injury.

“Estos padres han probado de todo, incluso potentes drogas psicotrópicas. … Es desgarrador. [Con el cannabis], estas familias han encontrado algo que creen que funciona”.

Dr. Gupta has shifted the cultural dialog —beginning with WEED, their original cannabis special that highlighted the journey of children with epilepsy finding great benefit from CBD. Massive mainstream viewership promises to bring similar attention to cannabis’ potential benefits for autism.

La investigación del cannabis para los síntomas del autismo ha pasado a la fase de estudio doble ciego controlada por placebo, relata el Dr. Sanjay Gupta. (CNN)

El especial está actualmente disponible a pedido a través de sistemas de cable/satélite, plataformas CNNgo y aplicaciones móviles de CNN.

Sociedad de Clínicos de Cannabis confiere digitalmente

Cannabis clinicians that actually treat autistic kids also collaborated like never before in the digital conference Navigating The Complexities of Autism & Cannabis: Facts vs. Myths Nov. 28. The Society of Cannabis Clinicians nonprofit brought together eight doctors and parents of autistic children to review research and outline treatments that were working.

Durante la sesión, muchos médicos (así como dos padres de pacientes autistas) hablaron sobre el éxito que estaban viendo con el uso del cannabis para el autismo y detallaron tratamientos con cannabinoides particulares que funcionaron bien.

THC vs CBD para el autismo

Los médicos informaron altos niveles de éxito en el mundo real con THC, el principal ingrediente activo del cannabis. Por el contrario, la mayoría de las investigaciones sobre cannabinoides en el autismo tienden a centrarse en el CBD. Eso se debe a que la medicina estadounidense desconfía del THC, dicen los médicos de cannabis.

“La literatura está muy por detrás de lo que estamos haciendo con los pacientes”, explicó la Dra. Bonni Goldstein MD, durante la conferencia. “Creo que parte de eso sigue siendo la dificultad de aceptar que el cannabis ayudará a estos niños”, agregó, y explicó que muchos todavía temen los efectos secundarios del THC.

Pero Goldstein y otros compartieron que sus pacientes autistas que usan THC están bien. “La mayoría de nosotros no vemos ningún efecto secundario significativo”.

El Dr. Justin Sulak también elogió los beneficios del THC para los pacientes autistas y explicó que el THC puede ser la mejor manera de explicar las deficiencias neuroquímicas observadas en los pacientes autistas. Específicamente, la anandamida de la molécula de 'bienaventuranza' del cuerpo. El THC funciona de manera similar a la anandamida.

Los pacientes médicos usan productos como la marca con licencia de California 'Care By Design', que ofrece proporciones específicas de CBD a THC. (Cuidado de cortesía por diseño)

“Tal vez el CBD podría usarse para simular la anandamida, pero creo que el THC será la herramienta más útil. Entonces, si alguien tiene esa deficiencia, por así decirlo, tiene sentido tratarlo con THC”.

Still, while THC was highlighted, doctors shared that a variety of different cannabinoids—including CBD, CBDA, THCA, and CBG —all seemed to offer beneficial effects for autistic patients.

Cannabis para la investigación del autismo redondeado

Los médicos también destacaron los numerosos estudios sobre cannabinoides para el TEA en 2021, otra gran victoria.

Dr. Patricia Frye, MD, the headliner for the conference, explained research dates to 2016, when a study concluded enhancing anandamide could help with autism. But research interest grew in the last few years.

"En 2021... tenemos cada vez más datos preclínicos y de observación, que analizan específicamente los riesgos y beneficios del cannabis y los cannabinoides en el tratamiento de afecciones tanto centrales como coexistentes".

Una docena de nuevos estudios analizaron los beneficios del cannabis para el autismo, lo que convierte a 2021 en un gran año de progreso.

El cannabis disminuyó los biomarcadores de daños

This November, Dr. Bonni Goldstein published new research showing cannabis cut levels of biomarkers for nerve-swelling, aggressiveness, and pain. Autistic patients’ abnormally high biomarkers came back into normal ranges after a year of treatment, Dr. Goldstein concludes.

Estos cambios en los biomarcadores se correlacionaron con una mejor conducta, según informes de padres de pacientes autistas.

El Dr. Goldstein dice que estas pruebas de biomarcadores podrían ayudar a medir la efectividad de los tratamientos con cannabinoides para el autismo.

2022 promete ver aún más avances en nuestra comprensión de cómo tratar el autismo. Para algunas de las 75 millones de personas estimadas con ASD en el mundo, las respuestas podrían cambiarles la vida.

Cannabinoides para el autismo: investigación clave

• Cannabis-Responsive Biomarkers: A Pharmacometabolomics-Based Application to Evaluate the Impact of Medical Cannabis Treatment on Children with Autism Spectrum Disorder; Cannabis and cannabinoid research; 2021; “biomarkers shifted toward the mean after [cannabis] treatment and can potentially quantify benefit at the metabolic level. These changes appear to be similar to the trend described in behavior surveys.”

• Cannabinoid treatment for autism: a proof-of-concept randomized trial; Molecular Autism; 2021; Disruptive behavior … was either “much or very much improved” in 49% [of patients] on whole-plant extract (20:1 CBD:THC tincture); “Further testing of cannabinoids in ASD is recommended.”

• Safety and Efficacy of Medical Cannabis in Autism Spectrum Disorder Compared with Commonly Used Medications; Cannabis and Cannabinoids Research; 2021; “CBD-rich medical cannabis seems to be an effective, tolerable, and relatively safe option for many symptoms associated with ASD, however, the long-term safety is unknown at this time.”

• Cannabinoids for people with ASD: a systematic review of published and ongoing studies; Brain Science; 2020; “The findings were promising, as cannabinoids appeared to improve some ASD-associated symptoms, such as problem behaviors, sleep problems, and hyperactivity, with limited cardiac and metabolic side effects.”

• Real life Experience of Medical Cannabis Treatment in Autism: Analysis of Safety and Efficacy; Nature; 2019; 30% of patients reported “significant improvement” on CBD+THC; “Cannabis in ASD patients appears to be well tolerated, safe and effective option to relieve symptoms associated with ASD.”

• Lower circulating endocannabinoid levels in children with autism spectrum disorder. Molecular Autism; 2019

• Brief Report: Cannabidiol-rich cannabis in children with autism spectrum disorder and severe behavioral problems-a retrospective feasibility study; Journal of Autism Developmental Disorder; 2019; “Following the cannabis treatment, behavioral outbreaks were much improved or very much improved in 61% of patients.”

• Effects of CBD-enriched cannabis sativa extract on autism spectrum disorder symptoms: an observational study of 18 participants undergoing compassionate use; Frontiers of Neurology; 2019; “​​The results reported here are very promising and indabidiol use in children with autism spectrum disorder to treat related symptoms and co-morbiditieer. Molecular Autism; 2018; “these data suggest that impaired anandamide signaling may be